Institute for Ophthalmic Research

Position

Director, Institute for Ophthalmic Research

Contacts details

Address

Centre for Ophthalmology
Institute for Ophthalmic Research
Roentgenweg 11
72076 Tuebingen

Phone, fax

Phone+49 7071 29-84021
Fax+49 7071 29-4560

WWW

Emailmarius.ueffing@uni-tuebingen.de
 
 

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Selected publications

Griciuc A, Aron L, Ueffing M.
"Looking into eyes: rhodopsin pathologies in Drosophila.",
Adv Exp Med Biol. 2012;723:415-23. PubMed PMID: 22183360.

Kortvely E, Ueffing M.
"Common mechanisms for separate maculopathies?",
Adv Exp Med Biol. 2012;723:61-6. PubMed PMID: 22183316.

Kiel C, Vogt A, Campagna A, Chatr-aryamontri A, Swiatek-de Lange M, Beer M, Bolz S, Mack AF, Kinkl N, Cesareni G, Serrano L, Ueffing M.
"Structural and functional protein network analyses predict novel signaling functions for rhodopsin.",
Mol Syst Biol. 2011 Nov 22;7:551. doi: 10.1038/msb.2011.83. PubMed PMID: 22108793.

Stanton CM, Yates JR, den Hollander AI, Seddon JM, Swaroop A, Stambolian D, Fauser S, Hoyng C, Yu Y, Atsuhiro K, Branham K, Othman M, Chen W, Kortvely E, Chalmers K, Hayward C, Moore AT, Dhillon B, Ueffing M, Wright AF.
"Complement factor D in age-related macular degeneration.",
Invest Ophthalmol Vis Sci. 2011 Nov 11;52(12):8828-34. Print 2011. PubMed PMID: 22003108; PubMed Central PMCID: PMC3230905.

Van Campenhout CA, Eitelhuber A, Gloeckner CJ, Giallonardo P, Gegg M, Oller H, Grant SG, Krappmann D, Ueffing M, Lickert H.
"Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.",
Dev Cell. 2011 Sep 13;21(3):479-91. PubMed PMID: 21920314.

Coene KL, Mans DA, Boldt K, Gloeckner CJ, van Reeuwijk J, Bolat E, Roosing S, Letteboer SJ, Peters TA, Cremers FP, Ueffing M, Roepman R.
The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase.",
Hum Mol Genet. 2011 Sep 15;20(18):3592-605. Epub 2011 Jun 17. PubMed PMID: 21685204.

Griciuc A, Aron L, Ueffing M.
"ER stress in retinal degeneration: a target for rational therapy?",
Trends Mol Med. 2011 Aug;17(8):442-51. Epub 2011 May 27. Review. PubMed PMID: 21620769.

Boldt K, Mans DA, Won J, van Reeuwijk J, Vogt A, Kinkl N, Letteboer SJ, Hicks WL, Hurd RE, Naggert JK, Texier Y, den Hollander AI, Koenekoop RK, Bennett J, Cremers FP, Gloeckner CJ, Nishina PM, Roepman R, Ueffing M.
"Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice.",
J Clin Invest. 2011 Jun 1;121(6):2169-80. doi: 10.1172/JCI45627. Epub 2011 May 23. PubMed PMID: 21606596; PubMed Central PMCID: PMC3104757.

Webb KJ, Coolen M, Gloeckner CJ, Stigloher C, Bahn B, Topp S, Ueffing M, Bally-Cuif L.
"The Enhancer of split transcription factor Her8a is a novel dimerisation partner for Her3 that controls anterior hindbrain neurogenesis in zebrafish.",
BMC Dev Biol. 2011 May 17;11:27. PubMed PMID: 21586122; PubMed Central PMCID: PMC3125270.

Del Río P, Irmler M, Arango-González B, Favor J, Bobe C, Bartsch U, Vecino E, Beckers J, Hauck SM, Ueffing M.
"GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration.",
Glia. 2011 May;59(5):821-32. doi: 10.1002/glia.21155. Epub 2011 Feb 28. PubMed PMID: 21360756

Griciuc A, Aron L, Roux MJ, Klein R, Giangrande A, Ueffing M. (2010)
"Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila.",
PLoS Genet. Aug 26;6(8). pii: e1001075.

Kinzel D, Boldt K, Davis EE, Burtscher I, Trümbach D, Diplas B, Attié-Bitach T, Wurst W, Katsanis N, Ueffing M, Lickert H. (2010).
"Pitchfork regulates primary cilia disassembly and left-right asymmetry.",
Dev Cell. 2010 Jul 20;19(1):66-77.

Hauck SM, Dietter J, Kramer RL, Hofmaier F, Zipplies JK, Amann B, Feuchtinger A, Deeg CA, Ueffing M. (2010).
"Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry.",
Mol Cell Proteomics. 9:2292-305

Hauck SM, Gloeckner CJ, Harley ME, Schoeffmann S, Boldt K, Ekstrom PA, Ueffing M.
"Identification of paracrine neuroprotective candidate proteins by a functional assay-driven proteomics approach.",
Mol Cell Proteomics. 2008 Jul;7(7):1349-61.

Deeg CA, Raith AJ, Amann B, Crabb JW, Thurau SR, Hauck SM, Ueffing M, Wildner G, Stangassinger M.
"CRALBP is a highly prevalent autoantigen for human autoimmune uveitis.",
Clin Dev Immunol. 2007;2007:39245.

Paquet-Durand F, Silva J, Talukdar T, Johnson LE, Azadi S, van Veen T, Ueffing M, Hauck SM, Ekström PA.
"Excessive activation of poly(ADP-ribose)polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse.",
J Neurosci. 2007 Sep 19;27(38):10311-9.

den Hollander AI, Koenekoop RK, Mohamed MD, Arts HH, Boldt K, Towns KV,Sedmak T, Beer M, Nagel-Wolfrum K, McKibbin M, Dharmaraj S, Lopez I, Ivings L,Williams GA, Springell K, Woods CG, Jafri H, Rashid Y, Strom TM, van der Zwaag B,Gosens I, Kersten FF, van Wijk E, Veltman JA, Zonneveld MN, van Beersum SE, Maumenee IH, Wolfrum U, Cheetham ME, Ueffing M, Cremers FP, Inglehearn CF, Roepman R. (2007).
"Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis.",
Nat Genet. Jul;39:889-95.

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