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Pathophysiology of Vision
Head
Prof. Dr. med. Eberhart Zrenner
Email: ezrenner [at] uni-tuebingen [dot] de
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| See also: | Clinic for Hereditary Retinal Degenerations |
Contact
Pathophysiology of Vision
Centre for Ophthalmology
Institute for Ophthalmic Research
Schleichstr. 12–16
72076 Tuebingen
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Team
Dr. Blanca Arango-Gonzáles blanca [dot] arango-gonzalez [at] klinikum [dot] uni-tuebingen [dot] de
Heval Benav heval [dot] benav [at] uni-tuebingen [dot] de
Dr. Antje Bernd antje [dot] bernd [at] med [dot] uni-tuebingen [dot] de
Sandra Bernhard-Kurz sandra [dot] bernhard-kurz [at] uni-tuebingen [dot] de
Silvia Bolz sylvia [dot] bolz [at] uni-tuebingen [dot] de
Wilhelm Durst wilhelm [dot] durst [at] uni-tuebingen [dot] de
Pietro Farinelli
Elke Feil elke [dot] feil [at] med [dot] uni-tuebingen [dot] de
Ulrike Fuchs ulrike [dot] fuchs [at] med [dot] uni-tuebingen [dot] de
Sabine Hailfinger sabine [dot] hailfinger [at] klinikum [dot] uni-tuebingen [dot] de
Wadood Haq wadood [dot] haq [at] klinikum [dot] uni-tuebingen [dot] de
Gudrun Härer gudrun [dot] haerer [at] med [dot] uni-tuebingen [dot] de
Tine Henes tine [dot] henes [at] arcor [dot] de
Stephanie Hipp stephanie [dot] hipp [at] med [dot] uni-tuebingen [dot] de
Barbara Huth barbara [dot] huth [at] klinikum [dot] uni-tuebingen [dot] de
Jasvir Kaur Jasvir [dot] Kaur [at] klinikum [dot] uni-tuebingen [dot] de
Angelikar Krickemeyer angelika [dot] krickemeyer-jagusch [at] klinikum [dot] uni-tuebingen [dot] de
PD Dr. Anne Kurtenbach anne [dot] kurtenbach [at] uni-tuebingen [dot] de
Gunnar Lotz mail [at] gunnarlotz [dot] com
Stine Mencl stine [dot] mencl [at] klinikum [dot] uni-tuebingen [dot] de
Dr. Francois Paquet-Durand francois [dot] paquet-durand [at] klinikum [dot] uni-tuebingen [dot] de
Dr. Tobias Peters tobias [dot] peters [at] stz-biomed [dot] de
Dr. Daniel Rathbun daniel [dot] rathbun [at] uni-tuebingen [dot] de
Dr. Robert Rejdak rrejdak [at] yahoo [dot] com
Ayse Sahaboglu Telgöz ayse [dot] sahaboglu-tekgoez [at] klinikum [dot] uni-tuebingen [dot] de
Dr. Ieva Sliesoraityte sliesoraityte [at] yahoo [dot] com
Dr. Katarina Stingl katarina [dot] stingl [at] med [dot] uni-tuebingen [dot] de
Torsten Straßer torsten [dot] strasser [at] gmx [dot] de
Dr. Felix Tonagel felix [dot] tonagel [at] med [dot] uni-tuebingen [dot] de
Dr. Dragana Trifunovic dragana [dot] trifunovic [at] klinikum [dot] uni-tuebingen [dot] de
Eric Tröger eric [dot] troeger [at] med [dot] uni-tuebingen [dot] de
Tao Wei tao [dot] wei [at] klinikum [dot] uni-tuebingen [dot] de
Dr. Annette Werner annette [dot] werner [at] uni-tuebingen [dot] de
Dr. Robert Wilke rghwilke [at] gmail [dot] com
Kirstin Wunderlich kirsten [dot] wunderlich [at] med [dot] lu [dot] se
Mission statement
The Professorship for Pathophysiology of Vision is focussed on retinal degeneration research. Its main goal is the translation of knowhow and results between basic and patient oriented research, thereby linking the various groups of the institute in translational research. An important part is the further development of Clinical Function Testing in order to access the function of the various parts of the ascending and descending visual pathway by refined methods of psychophysics, electrophysiology and imaging. This helps to differentiate the various forms of retinal diseases and to understand the disease mechanisms. Methods include Autofluorescence, Optical Coherence Tomography (OCT), Electroretinography, Rod-ERG, Cone-ERG, ON-OFF ERG, Multifocal Electroretinography ON-OFF Multifocal ERG, Electrooculography, refined Static and Kinetic Perimetry, Visual Evoked Cortical Potentials, and Pupillography.
We perform studies in patients with diseases of the retina and optic nerve, monitoring disease progress as well as effectiveness of therapies by such sensitive methods. Several experimental treatments are investigated in Clinical Studies; growth factors, electrostimulation and prosthetic chip technology for blind patients. Dr. Ieva Sliesoraityte as ophthalmological Scientist-Clinician cares especially for study patients together with Prof. Zrenner.
The Clinic for Hereditary Retinal Degeneration, The Color and Visual Psychophysics Group, the Biomedical Engineery Lab and the Retinal Function Research Group are directly linked to the Professorship for Pathophysiology of Vision.
Selected publications
Eberhart Zrenner, Karl Ulrich Bartz-Schmidt, Heval Benav, Dorothea Besch, Anna Bruckmann, Veit-Peter Gabel, Florian Gekeler, Udo Greppmaier, Alex Harscher, Steffen Kibbel, Johannes Koch, Akos Kusnyerik, Tobias Peters, Katarina Stingl, Helmut Sachs, Alfred Stett, Peter Szurman, Barbara Wilhelm and Robert Wilke: "Subretinal electronic chips allow blind patients to read letters and combine them to words" Proceedings of the Royal Society B, Advance online publication November 03, 2010. doi:10.1098/rspb.2010.1747
Wissinger B, Dangel S, Jägle H, Hansen L, Baumann B, Rudolph G, Wolf C, Bonin M, Koeppen K, Ladewig T, Kohl S, Zrenner E, Rosenberg T.-Cone: "Dystrophy with Supernormal Rod response Is Strictly Associated with Mutations in KCNV2." Investigative Ophthalmology & Visual Science. 2008. Vol:49 No:2, S.751-757
Langrová H, Jägle H, Zrenner E, Kurtenbach A. : "The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli. Visual Neuroscience." 2007. 24:805-816.
Shinoda K, Rejdak R, Schuettauf F, Blatsios G, Völker M, Tanimoto N, Olcay T, Gekeler F, Lehaci C, Naskar R, Zagorski Z, Zrenner E. : "Early electroretinographic features of streptozotocin-induced diabetic retinopathy." Clincal and Experimental Ophthalmology. 2007. 35, 9:847-54
Nagy D, Schönfisch B, Zrenner E, Jägle H : "Long-term follow-up retinitis pigmentosa patients with multifocal electroretinography." Invest Ophth Vis Sci 49, 4664-4671 (2008)
Thaler S, Fiedorowicz M, Rejdak R, Choragiewicz TJ, Sulejczak D, Stopa P, Zarnowski T, Zrenner E, Grieb P, Schuettauf F : "Neuroprotective effects of tempol on retinal ganglion cells in a partial optic nerve crush rat model with and without iron load." Exp Eye Res , 1-7 (2009)
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