Institute for Ophthalmic Research

Head

Prof. Dr. med. Eberhart Zrenner

Contact

Schleichstr. 12-16
72076 Tuebingen

Email ezrenner [at] uni-tuebingen [dot] de

Additional information

URL http://www.uak.medizin.uni-tuebingen.de

Mission statement

The aim of Clinical Function Testing is to access the func¬tion of the various parts of the ascending and descending visual pathway by refined methods of psychophysics, elec¬trophysiology and imaging in order to differentiate the various forms of retinal diseases and to understand the disease mechanisms. Methods include Autofluorescence, Optical Coherence Tomogra¬phy (OCT), Electroretinography, Rod-ERG, Cone-ERG, ON-OFF ERG, Multifocal Electroretinography ON-OFF Multifocal ERG, Electrooculography, refined Static and Kinetic Perimetry, Visual Evoked Cortical Potentials, and Pupillography.

We examine patients with diseases of the retina and optic nerve, differentiating the various forms including toxic or oncologic origin and monitoring of disease progress as well as effectiveness of therapies by such sensitive methods. Several experimental treatments are investigated in Clinical Studies; growth factors, electrostimulation and prosthetic chip technology for blind patients. Dr. Ieva Sliesoraityte as ophthalmological Scientist-Clinician cares especially for study patients together with Prof. Zrenner.

Selected publications

Wissinger B, Dangel S, Jägle H, Hansen L, Baumann B, Rudolph G, Wolf C, Bonin M, Koeppen K, Ladewig T, Kohl S, Zrenner E, Rosenberg T.-Cone
Dystrophy with Supernormal Rod response Is Strictly Associated with Mutations in KCNV2.
Investigative Ophthalmology & Visual Science. 2008. Vol:49 No:2, S.751-757 Langrová H, Jägle H, Zrenner E, Kurtenbach A. The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli. Visual Neuroscience. 2007. 24:805-816.

Shinoda K, Rejdak R, Schuettauf F, Blatsios G, Völker M, Tanimoto N, Olcay T, Gekeler F, Lehaci C, Naskar R, Zagorski Z, Zrenner E.
Early electroretinographic features of streptozotocin-induced diabetic retinopathy.
Clincal and Experimental Ophthalmology. 2007. 35, 9:847-54

Zrenner E.
Restoring neuroretinal function: new potentials.
Doc Ophthalmol. 2007. 115:56-59

Schuster A, Janecke AR, Wilke R, Schmid E, Thompson DA, Utermann G, Wissinger B, Zrenner E, Gal A.
The Phenotype of Early-Onset Retinal Degeneration in Persons with RDH12 Mutations.
Invest. Ophthalm. & Vis. Sci. 2006. Vol. 48, No. 4

Kurtenbach A, Mayser,H.M, Jägle H, Fritsche A, Zrenner E.
Hyperoxia, hyperglycemia, and photore¬ceptor sensitivity in normal and diabetic subjects.
Visual Neuroscience. 2006. 23, 651-661